By combining microfabrication and microtechnology with biological cells and tissue, new powerful opportunities for both fundamental research and technological applications open up. In this talk, I will introduce two different research projects connected by the same underlying idea of integrating microtechnology and biology: i) The modification of AFM-cantilevers with pathogenic bacteria to determine quantitative values for bacterial adhesion, and ii) the integration of human tissue into microfluidic devices to obtain organ-on-achip platforms.