Tue, 17/11/2015 - 14:15
,
Campus Saarbr├╝cken, Geb. E2 6, E04

Prof. Dr. Klaus Kroy
(
Host: Prof. Dr. Albrecht Ott
)
Physics Department, Leipzig University

Inelastic Biomechanics

Biomaterials are often classified as vicoelastic, but I will argue that this misses a crucial aspect, and that biomechanics is essentially damage mechanics, at heart. When deforming an animal cell or tissue, one can hardly avoid inducing the unfolding of protein domains, the unbinding of cytoskeletal crosslinkers, the breaking of weak sacrificial bonds, and the disruption of transient adhesions. These "inelastic" processes are often largely reversible rather than plastic, yet strongly dissipate. I will demonstrate their prevalence on multiple scales, from single biopolymers over cells to model tissues, and analyze them within a deliberately minimalistic but phenomenologically rich theoretical model.

http://dx.doi.org/10.1016/j.bbamcr.2015.06.017

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