Tue, 27/10/2015 - 14:15
,
Campus Saarbr├╝cken, Geb. E2 6, E04

Prof. Dr. Mark M. Somoza
(
Host: Prof. Dr. Albrecht Ott
)
Institute for Anorganic Chemistry, University of Vienna

High complexity arrays of DNA probes have been used extensively in genetics research to help understand gene expression and the regulation thereof, but microarrays of RNA and other natural or modified nucleic acids can be used to quantify binding interactions beyond hybridization. RNA binding proteins, for example, play major roles in the post-transcriptional regulation of gene expression. Evaluating the specificity landscape of RNA binding molecules is necessary to understand gene regulatory networks and to engineer molecules that can be used therapeutically to modify gene expression. I will describe how we us ideas drawn from physics, chemistry and biology to synthesize new types of microarrays. The new RNA microarrays, DNA-RNA chimeric microarrays and 2'-fluoro-ANA microarrays, and others, can be used to study how proteins and other relevant molecules recognize and bind to specific nucleic acid sequences or structures.

Upcoming Events

  • SFB 1027 Seminar

    Tue, 04/06/2024 - 14:15
    ,
    Campus SB, E2 6, E04

    Prof. Dr. Stefan Klumpp

    Physics in bacterial motility

  • SFB 1027 / INM - Seminar

    Wed, 05/06/2024 - 14:00
    ,
    Campus SB, D2 5, Leibniz Saal or online (Link below)

    Dr. Kevin Jahnke

    Engineering lipid membranes: From biophysical properties to biotechnological applications

  • IRTG Intro Lecture

    Tue, 11/06/2024 - 14:15
    ,
    Campus SB, Building E2 6, Room E.04

    Prof. Dr. Jochen Hub

    Everything You Always Wanted to Know About Molecular Dynamics Simulations* 

    (*But Were Afraid to Ask)

  • SFB 1027 Seminar

    Tue, 25/06/2024 - 14:15
    ,
    Campus SB, E2 6, E04

    Prof. Dr. Doris Heinrich

    t.b.a.

  • SFB 1027 summer camp

    Wed, 26/06/2024 - 09:00 to Fri, 28/06/2024 - 16:00
    ,
    BURG EBERNBURG 55583 Bad Kreuznach Bad M├╝nster am Stein Ebernburg

  • SFB 1027 Seminar

    Tue, 02/07/2024 - 14:15
    ,
    Campus SB, Building E2 6, Room E04

    Prof. Dr. Thomas Holstein

    t.b.a.

  • SFB 1027 Seminar

    Tue, 16/07/2024 - 14:15
    ,
    Campus SB, Building E2 6, Room E04

    Prof. Dr. Jona Kayser

    t.b.a.

 

 

 

 

 

 

 

 

 

 

 

 

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