Tue, 27/10/2015 - 14:15
,
Campus Saarbrücken, Geb. E2 6, E04

Prof. Dr. Mark M. Somoza
(
Host: Prof. Dr. Albrecht Ott
)
Institute for Anorganic Chemistry, University of Vienna

High complexity arrays of DNA probes have been used extensively in genetics research to help understand gene expression and the regulation thereof, but microarrays of RNA and other natural or modified nucleic acids can be used to quantify binding interactions beyond hybridization. RNA binding proteins, for example, play major roles in the post-transcriptional regulation of gene expression. Evaluating the specificity landscape of RNA binding molecules is necessary to understand gene regulatory networks and to engineer molecules that can be used therapeutically to modify gene expression. I will describe how we us ideas drawn from physics, chemistry and biology to synthesize new types of microarrays. The new RNA microarrays, DNA-RNA chimeric microarrays and 2'-fluoro-ANA microarrays, and others, can be used to study how proteins and other relevant molecules recognize and bind to specific nucleic acid sequences or structures.

Upcoming Events

  • SFB 1027 Seminar

    Tue, 12/11/2024 - 14:15
    ,
    Campus SB, Building E2 6, Room E04 or online via MS Teams

    Prof. Dr. Jamie Hobbs

    Using atomic force microscopy to understand the bacterial cell wall and its role in life, death, and antimicrobial resistance

  • SFB 1027 Seminar

    Tue, 19/11/2024 - 14:15
    ,
    Campus SB, Building E2 6, Room E04 or online via MS Teams

    Dr. Jona Kayser

    Drug Resistance Evolution as an Emergent Phenomenon in Heterogeneous Active Granular Matter

  • IRTG Intro Lecture

    Thu, 05/12/2024 - 14:00
    ,
    Campus SB, Building E2 9, Room 0.07 and online via MS Teams

    Prof. Dr. Bianca Schrul

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  • SFB 1027 Seminar

    Tue, 10/12/2024 - 14:15
    ,
    Campus SB, Building E2 6, Room E04 or online via MS Teams

    Prof. Dr. Marco Fritzsche

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