Tue, 06/09/2016 - 10:00
,
Saarbrücken, Campus, Geb. E2 6, 3.08

Prof. Dr. Sasa Svetina
(
Host: Prof. Dr. Christian Wagner
)
University of Ljubljana, Slovenia

Investigating cell functioning by theoretical analyses of cell-to-cell variability

Cell-to-cell variability in isogenic cell populations is analyzed by taking into consideration causal relations between the parameters that define the state of individual cells. A population of red blood cells is treated as an example to show that it is possible, from the relationships between standard deviations of distribution functions with respect to various cell parameters and their corresponding correlation coefficients, to unravel previously unidentified causal relations between these parameters. It is suggested that this approach can be employed in searching for the causal relations, which, in analogy with the process of self-reproduction of vesicles, could be required for the proper division of cells that grow and divide. On the basis of a vesicular origin of primordial life, it is concluded that the cell-to-cell variability could be a consequence of asymmetric vesicle divisions needed for the sustainability of early evolution.

 

Upcoming Events

  • IRTG Intro Lecture

    Tue, 27/07/2021 - 14:15
    ,
    Online lecture via MS Teams

    Dr. Yvonne Schwarz

    Knowing when to talk or stay silent - how do secretory cells communicate with each other?”

    Investigating the molecular mechanisms of exocytosis using state-of-the-art microscopy, biochemistry, mouse genetics and electrophysiology

  • IRTG Intro Lecture

    Tue, 19/10/2021 - 14:15
    ,
    Online lecture via MS Teams

    Jun.-Prof. Laura Aradilla-Zapata

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  • IRTG workshop

    Tue, 09/11/2021 - 09:00 to Wed, 10/11/2021 - 12:00
    ,
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    Dr. Christiane Kasack

    Making it happen: Time and self management for your PhD

  • IRTG Intro Lecture

    Tue, 07/12/2021 - 14:15
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    Prof. Dr. Sandra Iden

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