Fri, 30/06/2017 - 10:30
Campus Saarbrücken, Geb. C6 3, HS II

Prof. Ned Wingreen
Host: Prof. Dr. Heiko Rieger
Lewis-Sigler Institute & Department of Molecular Biology, Princeton University

Protein phase transitions in and out of cells

Biologists have recently come to appreciate that eukaryotic cells are home to a multiplicity of non-membrane bound compartments, many of which form and dissolve as needed for the cell to function. These dynamical “liquid droplets” enable many central cellular functions – from ribosome assembly, to RNA regulation and storage, to signaling and metabolism. While it is clear that these compartments represent a type of separated phase, what controls their formation, how specific biological components are included or excluded, and how these structures influence physiological and biochemical processes remain largely mysterious. I will discuss recent experiments on phase separated droplets both in vitro and in vivo, and will present theoretical results that highlight a novel “magic number” effect relevant to the formation and control of two-component phase separated liquid droplets.

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    Prof. Dr. Robert Ernst


  • IRTG Workshop

    Wed, 23/03/2022 - 09:00 to Fri, 25/03/2022 - 15:30

    Dr. Jan Brocher

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