Thu, 18/05/2017 - 14:00
,
Campus Saarbrücken, Geb. E2 6, E04

Dr. Jochen Hub
(
Host: Prof. Dr. Ludger Santen
)
Department of Molecular Structural Biology, Universität Göttingen

Biomolecular dynamics from simulation and experimental data

I present an overview of our ongoing research, covering various aspects of membrane biophysics up to the interpretation of low-resolution experimental data. The first part of the talk highlights how molecular dynamics (MD) simulations, complemented with free-energy calculations, may reveal the mechanisms and driving forces involved in transitions at biological membranes. Examples cover the energetics of membrane pore formation, lipid-protein interactions, and membrane channels. Second, I present new methods for combining MD simulations with low-resolution scattering data and Bayesian statistics, used to derive protein structures, ensembles, and ultrafast dynamics in solution. Several applications underline that the combination of simulation and experiment yields more detailed and more reliable insight than each of the methods alone.

Upcoming Events

  • IRTG Intro Lecture

    Tue, 19/10/2021 - 14:15
    ,
    Online lecture via MS Teams

    Jun.-Prof. Laura Aradilla-Zapata

    t.b.a.

  • IRTG workshop

    Tue, 09/11/2021 - 09:00 to Wed, 10/11/2021 - 12:00
    ,
    t.b.a.

    Dr. Christiane Kasack

    Making it happen: Time and self management for your PhD

  • IRTG Intro Lecture

    Tue, 07/12/2021 - 14:15
    ,
    t.b.a.

    Prof. Dr. Sandra Iden

    t.b.a.

 

 

 

 

 

 

 

 

 

 

 

 

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