Mon, 20/08/2018 - 11:00
,
Campus SB, INM (Geb. D2 5), Leibniz-Saal

Prof. Dr. Benedikt Berninger
(
Host: Prof. Dr. Aránzazu del Campo
)
Centre for Developmental Neurobiology, MRC Centre for Neurodevelopmental Disorders, King’s College London, UK

Engineering neurogenesis for the postnatal brain

We explore the possibilities of generating neurons where natural neurogenesis has ceased to occur, such as the postnatal or adult cerebral cortex. The approach we have taken is of lineage reprogramming glia or other brain-resident cells into induced neurons. Towards this end, we force the expression of developmentally relevant transcription factors to induce a neurogenic program. Here, I will discuss our efforts (1) to induce neurogenesis from glial cells in the postnatal mouse cortex in vivo, and (2) to decipher the molecular and cellular trajectories of cells undergoing conversion into induced neurons.

Upcoming Events

  • IRTG Intro Lecture

    Tue, 25/01/2022 - 14:15
    ,
    Teams

    Prof. Dr. Sandra Iden

    Bridging scales to study cell-cell communication in the skin

  • IRTG Intro Lecture

    Tue, 08/02/2022 - 14:15
    ,
    t.b.a.

    Prof. Dr. Robert Ernst

    t.b.a.

  • IRTG Workshop

    Wed, 23/03/2022 - 09:00 to Fri, 25/03/2022 - 15:30
    ,
    Online

    Dr. Jan Brocher

    BioVoxxel Workshop: Editing, Processing and Analysis of Scientific Image

 

 

 

 

 

 

 

 

 

 

 

 

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