Mon, 20/08/2018 - 11:00
,
Campus SB, INM (Geb. D2 5), Leibniz-Saal

Prof. Dr. Benedikt Berninger
(
Host: Prof. Dr. Aránzazu del Campo
)
Centre for Developmental Neurobiology, MRC Centre for Neurodevelopmental Disorders, King’s College London, UK

Engineering neurogenesis for the postnatal brain

We explore the possibilities of generating neurons where natural neurogenesis has ceased to occur, such as the postnatal or adult cerebral cortex. The approach we have taken is of lineage reprogramming glia or other brain-resident cells into induced neurons. Towards this end, we force the expression of developmentally relevant transcription factors to induce a neurogenic program. Here, I will discuss our efforts (1) to induce neurogenesis from glial cells in the postnatal mouse cortex in vivo, and (2) to decipher the molecular and cellular trajectories of cells undergoing conversion into induced neurons.

Upcoming Events

  • IRTG Intro Lecture

    Tue, 27/07/2021 - 14:15
    ,
    Online lecture via MS Teams

    Dr. Yvonne Schwarz

    Knowing when to talk or stay silent - how do secretory cells communicate with each other?”

    Investigating the molecular mechanisms of exocytosis using state-of-the-art microscopy, biochemistry, mouse genetics and electrophysiology

  • IRTG Intro Lecture

    Tue, 19/10/2021 - 14:15
    ,
    Online lecture via MS Teams

    Jun.-Prof. Laura Aradilla-Zapata

    t.b.a.

  • IRTG workshop

    Tue, 09/11/2021 - 09:00 to Wed, 10/11/2021 - 12:00
    ,
    t.b.a.

    Dr. Christiane Kasack

    Making it happen: Time and self management for your PhD

  • IRTG Intro Lecture

    Tue, 07/12/2021 - 14:15
    ,
    t.b.a.

    Prof. Dr. Sandra Iden

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