Tue, 30/04/2019 - 14:15
Campus SB, INM (Building D2 5), Leibniz-Saal

Prof. Dr. Phil Selenko
Host: Prof. Dr. Niels de Jonge
Weizmann Institute of Science, Rehovot, ISR

Looking at proteins in live cells with atomic resolution: from Science Fiction to Science Reality

Recent breakthroughs in optical and electron microscopy have changed the fields of Cellular and Structural Biology in a most profound manner. Ever more detailed information about the inner workings of cells is becoming available, revealing stunning new insights into molecular landscapes and their biological activities, at unprecedented levels of resolution. Besides these advancements in imaging modalities, complementary in situ methods are beginning to emerge as powerful tools in modern Cellular Structural Biology approaches. Here, I discuss how recent developments in in-cell NMR, EPR and single-molecule FRET spectroscopy contribute to our understanding of basic biological processes in live cells. Specifically, I outline how these techniques provide time-resolved atomic-resolution information about intracellular protein structures and functions, which cannot be obtained with any other method at this time.

Upcoming Events

  • Cell Physics 2023

    Mon, 09/10/2023 - 08:30 to Fri, 13/10/2023 - 17:00
    Campus SB, Building E2 2

    Cell Physics 2023 / Annual Meeting of the DGZ 2023

  • IRTG Intro Lecture

    Tue, 28/11/2023 - 14:00
    Campus SB, Building E2 9, Room 0.07

    Dr. Bin Qu

    Mechanisms employed by immune killer cells to locate and eliminate tumor cells

  • IRTG Intro Lecture

    Tue, 12/12/2023 - 14:15
    Campus SB, Building E2 9, Room 0.07

    Prof. Dr. Volkhard Helms

    Gene regulatory networks control the fate of biological cells













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