Tue, 13/08/2019 - 10:00
,
Campus SB, Building E2 6 Room E.04

Jun.-Prof. Dr. Marcel Lauterbach
(
Host: Prof. Dr. Christian Wagner
)
CIPMM, UdS (HOM)

Optics for Neuroscience

In this presentation I will demonstrate the benefit of modern optical techniques especially for neuroscience: After an introduction to STED microscopy the first part will present how Fast STED microscopy deciphers neurotransmitter-vesicle motion. Furthermore, it will be shown how integrating phase contrast into a STED microscope provides a second, label-free contrast channel. This allows for easy correlation of morphological structures with high-resolution fluorescence images. It is demonstrated that Spiral Phase Contrast in scanning confocal configuration yields improved optical contrast and allows quantitative phase measurements.

The last part will present microscopy in an unusual model system, turtles. Reptilian cerebral cortex contains 3 layers, similar to hippocampal and piriform cortices of mammals. Turtle cortex offers experimental advantages: it is resistant to anoxia and operates at room temperature. Cortical slabs can be cut in orientations that minimize lesions and keep inter-neuronal connections intact. The entire brain can even be extracted and kept in vitro for several days. Dendritic spines and calcium signaling can be advantageously studied in these preparations.

Upcoming Events

  • SFB 1027 Seminar

    Tue, 23/04/2024 - 14:00
    ,
    Campus SB, Building E2 6, Room E04

    Prof. Dr. Carsten Beta

    t.b.a.

  • SFB 1027 Seminar

    Tue, 30/04/2024 - 14:00
    ,
    Campus SB, Building E2 6, Room E04

    Prof. Dr. Abdou Rachid Thiam

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  • SFB 1027 Seminar

    Tue, 28/05/2024 - 14:00
    ,
    Campus SB, Building E2 6, Room E04

    Prof. Dr. Sabine Klapp

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  • IRTG Intro Lecture

    Wed, 29/05/2024 - 14:00
    ,
    Campus SB, Building E2 9, Room 0.07

    Prof. Dr. Karin Jabobs

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  • IRTG Intro Lecture

    Tue, 11/06/2024 - 14:00
    ,
    Campus SB, Building E2 6, Room E.04

    Prof. Dr. Jochen Hub

    Everything You Always Wanted to Know About Molecular Dynamics Simulations* 

    (*But Were Afraid to Ask)

  • SFB 1027 summer camp

    Wed, 26/06/2024 - 09:00 to Fri, 28/06/2024 - 16:00
    ,
    BURG EBERNBURG 55583 Bad Kreuznach Bad Münster am Stein Ebernburg

 

 

 

 

 

 

 

 

 

 

 

 

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