Wed, 01/03/2023 - 14:15
,
Campus Homburg, CIPMM Geb. 48 Auditorium and via MS Teams (link below)

Prof. Dr. Carsten Watzl
(
Host: Prof. Dr. Markus Hoth
)
Leibniz-Institut für Arbeitsforschung an der TU Dortmund (IfADo)

Attach, kill, release, repeat - mechanisms of NK cell serial killing

Natural killer (NK) cells are important innate lymphocytes for effective immune reactions against infections and cancer. Cytokine production and cellular cytotoxicity are important effector functions of NK cells. In the past we have investigated many aspects of NK cell cytotoxicity. These include the attachment to target cells, the stimulation of NK cells by activating and inhibitory receptors, the use of granule and death-receptor-mediated killing pathways, the detachment from target cells, and the serial killing of multiple targets. In my talk I will give an overview about our recent insights into these different aspects of NK cell cytotoxicity.

Link to online presentation: Click here to join the meeting

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