B2 -

Bacterial adhesion and biofilm formation: Physical processes at interfaces


The interaction of microorganisms with biologic or artificial surfaces is a key factor in disease pathogenesis. The goal of this project is to use biophysical methods in combination with microbial genetic engineering for the physical modeling of bacterial cell processes resulting in substrate colonization. Based on our recent findings made within the first funding period, we will next determine the initial adhesion of viable bacteria to complex biological surfaces. Insights in these phenomena may help to explore new avenues in prevention and treatment of major bacterial infections.













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