Bio-inspired control of oral biofilms: Pellicle management on dental surfaces
This project aims to develop and investigate novel bioinspired strategies for the management of intraoral biofilm formation. The main objective is to elucidate the process of initial bio-adhesion taking place on natural tooth surfaces at the molecular level, and to modify the physiological pellicle by combinations of biomimetic apatite particles, polyphenols and essential oils or by nano-carriers (casein micelles, lipid nanoparticles) loaded with plant extracts.